When you first launch Office Click to Run or Office 2016, you will get a First things first dialog box come up like below. Users will always click accept, what other choice do they have?
[HKEY_CURRENT_USER\SOFTWARE\Microsoft\Office\16.0\Registration]
"AcceptAllEulas"=dword:00000001
If you want to roll it out to lots of users then you can use Group Policy Preferences. You can use my guide at the link below if you want to find out how to do it.
Create, Delete, Modify Registry Keys Using Group Policy Preferences